Amy Riek, MD

Associate Professor of Medicine and Medical Director of Clinical Operations


Amy was raised in New Hampshire and moved to Wisconsin with her family to finish high school. She received a BS in biochemistry and molecular biology at the University of Wisconsin in Madison in 2001. She attended Washington University in St. Louis for medical school and stayed on to train in Internal Medicine at Barnes-Jewish Hospital. She completed her fellowship in Endocrinology and Metabolism at Washington University in St. Louis.

Research Interests

Vitamin D is well-recognized for its role in calcium homeostasis through its effects on intestinal calcium absorption and osteoclast stimulation. Less well-recognized, however, are the additional targets of vitamin D in many other tissues, including the heart and vascular system, which may have implications in the management of vascular disease and atherosclerosis. The actions of vitamin D are mediated by vitamin D receptor (VDR), a nuclear receptor which binds 1α, 25-dihydroxcholecalciferol, and interacts with vitamin D response elements to alter the expression of their target genes. We are currently using animal models to determine the role of vitamin D in vascular disease.

Awards and Honors

Dr. Riek was selected as a 2009 recipient of the Knowlton Incentive for Excellence Award. The Knowlton Fund recognizes five internal medicine house staff physicians each year who best exemplify balancing compassionate care with a dedication to the science of internal medicine.