Semenkovich publishes research on how parent-of-origin effects shape metabolic traits

Clay F. Semenkovich, MD

In March, Clay F. Semenkovich, MD and colleagues had their work titled “Parent-of-origin effects propagate through networks to shape metabolic traits,” published in “eLife.”  Parent-of-origin effects (POE) are a class of genetic effects transmitted from parents to their offspring and are “unexpectedly common in complex traits, including metabolic and neurological traits.” Environmental factors can modify […]

Semenkovich and collaborators publish in Proceedings of the National Academy of Sciences

Clay F. Semenkovich, MD

On January 11, Clay F. Semenkovich, MD and collaborators had their research titled, “FASN-dependent de novo lipogenesis is required for brain development,” published in the “Proceedings of the National Academy of Sciences.”  De novo lipogenesis is a metabolic pathway, which is essential to governing progenitor function through supplying energy and providing molecular building blocks that generate cells. […]