Earlier this year, Jeffrey Millman, PhD received sub-award funding from JDRF to support his lab’s extensive research in advancing diabetes cell replacement therapy. The scarcity of pancreas donors has severely limited the supply of insulin-producing islets for clinical transplantation, prompting the exploration of alternative sources. Dr. Millman has pioneered approaches to generate lab-grown islets from […]
On May 8, Nathaniel Hogrebe, PhD; Jeffrey Millman, PhD; and collaborators published the research article “Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques” in Nature Biotechnology demonstrating that immune-engineered induced pluripotent stem cells (iPSCs) can survive long-term without provoking an immune reaction. These hypoimmune iPSCs were engineered to lack the […]
Dr. Jeffrey Millman has received a renewal of his NIH R01 grant titled “Studying the Role of the Microenvironment on Differentiation and Maturation of Beta Cells”, providing 4 years of additional support into his research. Human pluripotent stem cells (hPSCs) hold great potential as a renewable source of insulin-producing islets for diabetes treatment. While transplantation […]