Tag: Maria Remedi

Semenkovich Lab and collaborators show the evolution of type 2 diabetes through APT1 deficiency 

On January 11, Semenkovich Lab and collaborators, had their research titled “Palmitoylation couples insulin hypersecretion with β cell failure in diabetes,” published in “Cell Metabolism.”  Hyperinsulinemia is known to often come before type 2 diabetes. In the study, they explain how acyl-protein thioesterase 1 (APT1) knockdown in nondiabetic islets causes insulin hypersecretion.  By using palmitoylation proteomics, their […]

Remedi publishes on ATP-sensitive potassium channels in hyperinsulinism and type 2 diabetes

On February 23, Maria S. Remedi, PhD and collaborators had their findings published in “Diabetes,” titled “ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm?” The article is meant to assess if adenosine triphosphate-sensitive potassium (KATP) channels are a new and effective way of thinking, in regard to hyperinsulinism and type […]