American Society for Clinical Investigation honors physician-scientists (Links to an external site)
Category: Featured News
Herrick publishes study on social determinants in health documentation
In February, Cynthia Herrick, MD and colleagues had their research titled “The adoption of social determinants of health documentation in clinical settings,” published in “Health Services Research.” The study was focused on understanding “the frequency of social determinants of health (SDOH) diagnosis codes (Z-codes) within the electronic health record for patients with prediabetes and diabetes […]
Crewe publishes research on the effects of cav1 on insulin-independent glucose uptake
In December, Clair Crewe, PhD and colleagues had their research titled “Deficient Caveolin-1 Synthesis in Adipocytes Stimulates Systemic Insulin-Independent Glucose Uptake via Extracellular Vesicles,” published in “Diabetes.” Within plasma membrane invaginations, is an essential structural and signaling component called cavelolin-1 (cav1). It is also abundantly found in adipocytes. Throughout the study, Crewe and collaborators analyze […]
Silverstein discusses patient care for brain tumor patients
In a recent video by the Siteman Cancer Center, Julie Silverstein, MD discusses what brain tumor patients can expect from the extended care team. Silverstein directs the Washington University Pituitary Center, alongside neurosurgeon Albert H. Kim, MD, PhD. The informative video is a six-chapter series, where Silverstein also shares her unique role, why she became an […]
Urano Lab receives funding to test the efficacy of a Sigma 1 receptor agonist pridopidine
The Snow Foundation, the Ellie White Foundation, and the Unravel Wolfram Syndrome have donated funds to the research lab of Fumihiko Urano, MD, PhD. The research team will use the funds to test the efficacy of a Sigma 1 receptor agonist, pridopidine, developed by Prilenia in pre-clinical models of Wolfram syndrome. Successful completion of this […]
Bernal-Mizrachi shares perspective on the relationship between vitamin D supplements and obesity
On January 17, Carlos Bernal-Mizrachi, MD was featured in a recent Healio article, titled “Adults with overweight, obesity may have decreased response to vitamin D supplements.” The article discusses a post hoc analysis of data from a VITAL trial. Specifically, how the effect of vitamin D supplements on 25-hydroxyvitamin D levels could be weakened for those […]
Zhang publishes research on the diagnosis and monitoring of onchocerciasis
In January, Qiang Zhang, PhD and collaborators had their research titled “Direct Proteomic Detection and Prioritization of 19 Onchocerciasis Biomarker Candidates in Humans,” published in “Molecular and Cellular Proteomics.” Onchocerca volculus is the causative agent of onchocerciasis. Which affects over 20 million people, causing severe dermatitis and ocular conditions, including blindness. As current treatments do […]
Powers Carson publishes article on glycated albumin
On January 31, Jennifer Powers Carson, PhD published an article with AACC Academy, titled “Glycated Albumin – What do laboratorians need to know to be ready for this testing?” It is evident that there is a need for more translational studies on glycated albumin (GA) to determine whether it offers improvements to diabetic care, and […]
Hogrebe receives JDRF Transition Award
On February 1, Nathaniel Hogrebe, PhD received a $110,000 JDRF Transition Award. The award is meant to assist recipients of the JDRF Advanced Postdoctoral Fellowship to advance into a faculty position as they continue with diabetes-related research. Hogrebe transitioned from Postdoctoral Research Scholar in Millman Lab, to Instructor in Medicine on February 1. I am very […]
Semenkovich Lab and collaborators show the evolution of type 2 diabetes through APT1 deficiency
On January 11, Semenkovich Lab and collaborators, had their research titled “Palmitoylation couples insulin hypersecretion with β cell failure in diabetes,” published in “Cell Metabolism.” Hyperinsulinemia is known to often come before type 2 diabetes. In the study, they explain how acyl-protein thioesterase 1 (APT1) knockdown in nondiabetic islets causes insulin hypersecretion. By using palmitoylation proteomics, their […]