John T. Milliken Department of Internal Medicine
Thomas J. Baranski, MD, PhD has received an NIH R01 award. This is a mutual PI award with Mike Provence, PhD and Heather Lawson, PhD in the Department of Genetics. The researchers will use a high-throughput method to manipulate hundreds of suspected genes to hone in on the biology behind the human findings, which could lead to […]
Dr. Herrick and collaborators published their article in the Journal of General Internal Medicine on September 1, 2020. In their study, the researchers compared cost coping behaviors and cost conversation strategies among individuals with multiple chronic conditions, comparing participants with and without diabetes. The authors stated, “Most strikingly, while individuals with diabetes were more likely […]
Congratulations to our physicians recognized on the 2020-2021 Best Doctors List. Founded in 1989 by doctors affiliated with Harvard University School of Medicine, Best Doctors is a leader in helping people get the best medical care. Washington University Physicians has more Best Doctors than any other physician group in St. Louis. Of the 1,280 St. Louis-area physicians on the […]
Researchers at Washington University have been generating insulin-producing islets in the laboratory from human stem cells. This approach promises a virtually unlimited supply of replacement insulin-producing tissues to functionally cure patients with diabetes. However, cell-derived islets are immature compared to islets from the body, lacking the expression of genes associated with maturation. Here, a team […]
Leonardo Velazco-Cruz, BS and Madeleine Goedegebuure, BS from the Millman Lab had their review article on β cell development and functional maturation published in Frontiers in Bioengineering and Biotechnology. “Human stem cell-derived β (SC-β) cells have the potential to revolutionize diabetes treatment through disease modeling, drug screening, and cellular therapy. SC-β cells are likely to […]
Doctoral student, Punn Augsornworawat, MS and Dr. Millman published a review article on single-cell RNA sequencing to investigate pancreas development and diabetes. From the authors abstract, “The islets of Langerhans are complex tissues composed of several cell types that secrete hormones. Loss or dysfunction of the insulin-producing β cells leads to dysregulation of blood glucose […]
We are pleased to announce that Barnes Jewish Hospital and Washington University School of Medicine have been ranked in the top 10 nationally in the specialty of adult Diabetes and Endocrinology for 2020-2021 by U.S. News & World Report. Congratulations to our outstanding and dedicated physicians, nurses and clinical staff who continue to deliver exceptional […]
The authors concluded, “These results suggest that endothelial depalmitoylation is regulated by the metabolic milieu and controls plasma membrane partitioning to maintain vascular homeostasis.” Authors include Sangeeta Adak, Mohamed Zayed, Li Yin, Chu Feng, Sarah L. Speck, Rahul S. Kathayat, Qiang Zhang, and Bryan C. Dickinson. Endothelial Palmitoylation Cycling Coordinates Vessel Remodeling in Peripheral Artery […]
