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Jasim and colleagues review thyroid gland fine-needle aspiration 

On March 23, Sina Jasim, MD, MPH, and colleagues had their book chapter titled “Fine-Needle Aspiration of the Thyroid Gland,” published by “Endotext [Internet].” The chapter is part of a series and is available online. 

“Thyroid nodules are common in clinical practice and the majority are benign with the risk of malignancy varying from 7 to 15%. Clinical evaluation includes careful history and physical examination, laboratory tests, neck ultrasound, and a fine-needle aspiration (FNA).” Throughout the review, Jasim and colleagues discuss ultrasound-guided FNA techniques, FNA result classifications, and the conventional classifications of diagnostic smears.  

In addition, the authors dissect the Bethesda System, a 6-category classification system used for reporting diagnostic criteria in thyroid cytopathy, and briefly review the utility of current United States stratification systems and molecular testing in differentiating benign from malignant thyroid nodules. 

Jasim S, Dean DS, Gharib H. Fine-Needle Aspiration of the Thyroid Gland. 2023 Mar 23. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905400