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McNerney and Jasim discuss the long-term endocrine effects of cancer treatment 

On October 10, 2023, Kyle P. McNerney, MD of the Department of Pediatrics at Washington University School of Medicine and Sina Jasim, MD of the Division of Endocrinology, Metabolism and Lipid Research, had their book chapter titled “Long-Term Effects of Cancer Treatment” published in Familial Endocrine Cancer Syndromes: Navigating the Transition of Care for Pediatric and Adolescent Patients.  

There is a high prevalence of endocrine-specific disorders that arise in the survivors of childhood cancer. Throughout the chapter, the authors discuss how the increased risk “may be attributable to disease-specific alterations in endocrine function or due to adverse effects of treatment with radiation, surgery, or chemotherapy.” 

Furthermore, Drs. McNerney and Jasim express the importance of monitoring long-term health outcomes, to diagnose and treat endocrine disorders that may arise, including hypothalamic/pituitary hormone deficiencies, growth abnormalities, obesity and metabolic disorders. Stating that the “standardization of long-term follow-up and the use of patient-facing digital health interventions may offer novel ways to improve health behaviors and outcomes.” 

McNerney, K.P., Jasim, S. (2023). Long-Term Effects of Cancer Treatment. In: Hannah-Shmouni, F. (eds) Familial Endocrine Cancer Syndromes. Springer, Cham. https://doi.org/10.1007/978-3-031-37275-9_10