On November 14, Dr. Clay F. Semenkovich, Chief of the Division of Endocrinology, Metabolism and Lipid Research, participated in World Diabetes Day by joining in a YouTube series hosted by Cell Metabolism. In the series, Dr. Semenkovich discusses the paper “Palmitoylation couples insulin hypersecretion with β cell failure in diabetes,” published on February 7, 2023, […]
On February 7, Guifang Dong, PhD; Sangeeta Adak, PhD; Qiang Zhang, PhD; Chu Feng, MS; Li Yin, MD; Sarah Speck; Shuntaro Morikawa; Rie Asada, PhD; Fumihiko Urano, MD, PhD; Maria Remedi, PhD; Xiaochao Wei, PhD; Clay Semenkovich, MD; and collaborators had their work published in “Cell Metabolism.” “Hyperinsulinemia often precedes type 2 diabetes,” and palmitoylation, […]
On January 11, Semenkovich Lab and collaborators, had their research titled “Palmitoylation couples insulin hypersecretion with β cell failure in diabetes,” published in “Cell Metabolism.” Hyperinsulinemia is known to often come before type 2 diabetes. In the study, they explain how acyl-protein thioesterase 1 (APT1) knockdown in nondiabetic islets causes insulin hypersecretion. By using palmitoylation proteomics, their […]
On June 15, Clay F. Semenkovich, MD and collaborators had their research titled “Altered Peroxisome Proliferator-Activated Receptor Alpha Signaling in Variably Diseased Peripheral Arterial Segments,” published in “Frontiers in Cardiovascular Medicine.” “Peripheral atherosclerosis that accumulates in the extracranial carotid and lower extremity arteries can lead to significant morbidity and mortality. However, atherosclerotic disease progression is […]