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Semenkovich describes model of type 2 diabetes in video series for World Diabetes Day

On November 14, Dr. Clay F. Semenkovich, Chief of the Division of Endocrinology, Metabolism and Lipid Research, participated in World Diabetes Day by joining in a YouTube series hosted by Cell Metabolism.

In the series, Dr. Semenkovich discusses the paper “Palmitoylation couples insulin hypersecretion with β cell failure in diabetes,” published on February 7, 2023, in volume 35, issue 2, of Cell Metabolism.

Written in collaboration with Semenkovich Lab members and colleagues, the paper shows how altered palmitoylation in mice can model the evolution of some forms of human type 2 diabetes.

Guifang Dong, Sangeeta Adak, George Spyropoulos, Qiang Zhang, Chu Feng, Li Yin, Sarah L. Speck, Zeenat Shyr, Shuntaro Morikawa, Rie Asada Kitamura, Rahul S. Kathayat, Bryan C. Dickinson, Xue Wen Ng, David W. Piston, Fumihiko Urano, Maria S. Remedi, Xiaochao Wei, Clay F. Semenkovich. Palmitoylation couples insulin hypersecretion with β cell failure in diabetes. Cell Metabolism. Volume 35, Issue 2. 2023. Pages 332-344.e7. SSN 1550-4131. https://doi.org/10.1016/j.cmet.2022.12.012