Earlier this year, Jeffrey Millman, PhD received sub-award funding from JDRF to support his lab’s extensive research in advancing diabetes cell replacement therapy. The scarcity of pancreas donors has severely limited the supply of insulin-producing islets for clinical transplantation, prompting the exploration of alternative sources. Dr. Millman has pioneered approaches to generate lab-grown islets from […]
On May 4, Nathaniel Hogrebe, PhD; Matthew Ishahak, PhD; and Jeffrey Millman, PhD had their review titled “Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes,” published in Cell Stem Cell. In diabetes treatment, there is great potential for islet-like endocrine clusters from human pluripotent stem cells (hPSCs) to provide a limitless […]
On September 22, Jeffrey R. Millman, PhD and Fumihiko Urano, MD, PhD, along with colleagues, had their research titled, “Multidimensional analysis and therapeutic development using patient iPSC–derived disease models of Wolfram syndrome,” published in “JCI Insight.” “Wolfram syndrome is a rare genetic disorder largely caused by pathogenic variants in the WFS1 gene and manifested by diabetes mellitus, […]
On July 17, Jeffrey R. Millman, PhD was featured in AP News’ article titled, “High-flying experiment: Do stem cells grow better in space?” As scientists see great promise in stem cell research, “researcher Dhruv Sareen’s own stem cells are now orbiting the Earth. The mission? To test whether they’ll grow better in zero gravity.” […]
On March 16, Jeffrey R. Millman, PhD and collaborators had their research titled “Differential Function and Maturation of Human Stem Cell-Derived Islets After Transplantation,” published in issue 3 of “Stem Cells Translational Medicine.” It is evident that cell replacement therapy is a potential treatment for patients with diabetes. One possible renewable source of replacement cells are stem-cell […]