On January 17, Carlos Bernal-Mizrachi, MD was featured in a recent Healio article, titled “Adults with overweight, obesity may have decreased response to vitamin D supplements.”
The article discusses a post hoc analysis of data from a VITAL trial. Specifically, how the effect of vitamin D supplements on 25-hydroxyvitamin D levels could be weakened for those who have higher BMI levels.

Bernal Mizrachi offers his perspective, stating that the study “lays the groundwork for further studies in the vitamin D-deficient population to evaluate the influence of BMI on biomarkers of vitamin D metabolism after supplementation and determine whether these are better predictors of clinical response in interventional trials.”
Adults with overweight, obesity may have decreased response to vitamin D supplements