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Bernal-Mizrachi shares perspective on the relationship between vitamin D supplements and obesity 

On January 17, Carlos Bernal-Mizrachi, MD was featured in a recent Healio article, titled “Adults with overweight, obesity may have decreased response to vitamin D supplements.” 

The article discusses a post hoc analysis of data from a VITAL trial. Specifically, how the effect of vitamin D supplements on 25-hydroxyvitamin D levels could be weakened for those who have higher BMI levels. 

Data were derived from Tobias DK, et al. JAMA Netw Open. 2023; doi:10.1001/jamanetworkopen.2022.50681.

Bernal Mizrachi offers his perspective, stating that the study “lays the groundwork for further studies in the vitamin D-deficient population to evaluate the influence of BMI on biomarkers of vitamin D metabolism after supplementation and determine whether these are better predictors of clinical response in interventional trials.” 

Adults with overweight, obesity may have decreased response to vitamin D supplements