Recently, Fumihiko Urano, MD, PhD joined “It Happened to Me” podcast hosts Cathy Gildenhorn and Beth Glassman to discuss Wolfram syndrome and his ongoing research. Dr. Urano is the director of the Wolfram Syndrome International Registry & Clinical Study and the doctor of Cathy, who has a variant of the disease. Wolfram syndrome is an […]
On September 11, 2023, Fumihiko Urano, MD, PhD and Sina Jasim, MD, MPH, were featured on the AACE’s podcast titled “Episode 41: AACE Clinical Case Report on Wolfram Syndrome.” As the editor in chief of AACE Clinical Case Reports, Dr. Jasim welcomes Wolfram syndrome expert Dr. Urano, to discuss his recent case report, published by […]
On September 6, 2023, Sister Grace Miriam Usala, MS, MD; Alberto Sobrero, BSc; Amy Riek, MD; Janet B. McGill, MD, MA, FACE, FACP and Fumihiko Urano, MD, PhD had their clinical case report titled “Cystic and Atrophic Kidneys, Atrophic Pancreas, Arcuate Uterus, and Diabetes Mellitus Associated With Deletion of HNF1β Gene,” published in AACE Clinical […]
On March 30, Cris Brown, BA and Fumihiko Urano, MD, PhD of Urano Lab, alongside colleagues from Belgique, Belgium and Italy, had their article titled “GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models,” published in Diabetologia. Wolfram syndrome is a rare autosomal recessive disorder that commonly manifests itself in the form […]
On February 7, Guifang Dong, PhD; Sangeeta Adak, PhD; Qiang Zhang, PhD; Chu Feng, MS; Li Yin, MD; Sarah Speck; Shuntaro Morikawa; Rie Asada, PhD; Fumihiko Urano, MD, PhD; Maria Remedi, PhD; Xiaochao Wei, PhD; Clay Semenkovich, MD; and collaborators had their work published in “Cell Metabolism.” “Hyperinsulinemia often precedes type 2 diabetes,” and palmitoylation, […]
In April, Fumihiko Urano, MD, PhD was featured in the documentary “Colorado Voices: Ellie White,” to raise awareness of the rare genetic disorder, Wolfram syndrome. The short documentary was published by Rocky Mountain PBS and tells the story of Colorado college student Ellie White, who lives with the disorder. Although the disorder is very rare […]
The Snow Foundation, the Ellie White Foundation, and the Unravel Wolfram Syndrome have donated funds to the research lab of Fumihiko Urano, MD, PhD. The research team will use the funds to test the efficacy of a Sigma 1 receptor agonist, pridopidine, developed by Prilenia in pre-clinical models of Wolfram syndrome. Successful completion of this […]
On January 11, Semenkovich Lab and collaborators, had their research titled “Palmitoylation couples insulin hypersecretion with β cell failure in diabetes,” published in “Cell Metabolism.” Hyperinsulinemia is known to often come before type 2 diabetes. In the study, they explain how acyl-protein thioesterase 1 (APT1) knockdown in nondiabetic islets causes insulin hypersecretion. By using palmitoylation proteomics, their […]