Augsornworawat receives award for research on single-cell sequencing of stem cell-derived islets

On May 2, Punn Augsornworawat, PhD received the Biomedical Engineering Outstanding Research Award for his work in the single-cell sequencing of stem cell-derived islets for diabetes cell therapy.  Augsornworawat joined the Millman Lab back in 2018 as a doctoral student in the Biomedical Engineering PhD program. His interests lie in using bioinformatics to study islet development […]

Millman publishes research on insulin-producing SC-islets after transplantation

On March 16, Jeffrey R. Millman, PhD and collaborators had their research titled “Differential Function and Maturation of Human Stem Cell-Derived Islets After Transplantation,” published in issue 3 of “Stem Cells Translational Medicine.”  It is evident that cell replacement therapy is a potential treatment for patients with diabetes. One possible renewable source of replacement cells are stem-cell […]

Lodhi receives $2M grant to study mitochondrial dynamics in brown fat-mediated thermogenesis

Irfan Lodhi, PhD

Irfan Lodhi, associate professor of medicine at the School of Medicine, received a $1.95 million grant from the National Institute of Health for research titled “Mitochondrial dynamics and the control of adipose tissue thermogenesis.”  Targeting brown fat function to promote thermogenesis and increase energy expenditure is a promising strategy to treat obesity and the associated […]

McKee discusses strategies for personalized type 2 diabetes treatment

On April 1, ReachMD released an interview featuring Alexis McKee, MD in their “Diabetes Discourse” series. The discussion is titled, “Collaborative Goal Setting in Type 2 Diabetes: Tailoring Treatment Plans for Patients.”  In the 10-minute interview, McKee discusses communication strategies that can be used to create personalized treatment plans and to improve adherence among patients […]

McGill receives national Outstanding Physician Clinician in Diabetes Award

On March 14, the American Diabetes Association announced the recipients of the 2022 National Scientific and Health Care Achievement Awards. Janet B. McGill, MD, MA, FACP was named as the recipient of the 2022 Outstanding Physician Clinician in Diabetes Award.   The award recognizes Dr. McGill’s meritorious contributions to diabetes clinical practice for over 30 years. […]

Millman publishes research characterizing human stem cell-derived islets with multiomics

On February 27, Jeffrey R. Millman, PhD and collaborators had their research findings published in “bioRxiv,” titled “Multiomic profiling defines cell fate plasticity of in vitro-derived islets.”  For patients with type 1 diabetes, insulin-secreting β-cells within the pancreatic islets of Langerhans cells are lost. There is limited understanding of the molecular events that govern the process […]

Semenkovich and Rajagopal publish article on ‘fatty retina’ linking to vision loss in diabetes

Clay F. Semenkovich, MD and Rithwick Rajagopal, MD, PhD recently published an article in Lipid Maps titled, “’Fatty retina’ – A root cause of vision loss in diabetes?”  “Diabetes is a disease of broadly disordered metabolism that affects how cells handle lipids, amino acids and signaling networks that regulate growth and proliferation, in addition to […]

Carmichael publishes article on GLP-1 Receptor Agonists

Kim A. Carmichael, MD published a recent article in the February 2022 issue of Consultant 360 titled, “What Do You Need to Know About GLP-1 Receptors Agonists?”  GLP-1 agonists, otherwise known as glucagon-like peptide 1 agonists, are an important class of medications for patients diagnosed with type 2 diabetes.  As the author and series editor, […]

Millman featured in Sounds of Science podcast: A Possible Cure for Diabetes

On February 1, Jeffrey R. Millman, PhD joined Mary Parker on Eureka’s Sounds of Science podcast, episode 45: “A Possible Cure for Diabetes.”  In this episode, Millman discusses what work the Millman Lab is doing to find a cure for diabetes through cellular replacement therapy. The podcast also features Laura Gee, a type 1 diabetic patient […]

Hughes Lab publishes research on primary cilia’s role in insulin secretion

On December 14, Jing W. Hughes, MD, PhD and Hughes Lab members had their research titled, “Islet primary cilia motility controls insulin secretion,” published in “bioRxiv.”   “Primary cilia are specialized cell-surface organelles that mediate sensory perception and, in contrast to motile cilia and flagella, are thought to lack motility function.” People with type 2 diabetes […]