Tag: diabetes

Hogrebe and Millman contribute to new study on immune-engineered stem cells  

On May 8, Nathaniel Hogrebe, PhD; Jeffrey Millman, PhD; and collaborators published the research article “Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques” in Nature Biotechnology demonstrating that immune-engineered induced pluripotent stem cells (iPSCs) can survive long-term without provoking an immune reaction.   These hypoimmune iPSCs were engineered to lack the […]

Dusso and colleagues highlight a distinct contribution of klotho to cardiac and renal fibrosis in diabetes 

On March 9, Adriana S. Dusso, PhD and colleagues had their work titled “Role of Klotho and AGE/RAGE-Wnt/β-Catenin Signalling Pathway on the Development of Cardiac and Renal Fibrosis in Diabetes,” published in the International Journal of Molecular Sciences.  A key influence on the development of long-term diabetic complications, including cardiac and renal dysfunction, is fibrosis.  […]

McKee, McGill and Jones publish letter to the editor on insulin dosing safety 

In April, Alexis McKee, MD; Janet B. McGill, MD; and current fellow, Kai Jones, MD, had their letter to the editor titled “Insulin Dosing Safety in CKD,” published in volume 8, issue 4 of Kidney International Reports.  In the letter, the authors highlight a recent manuscript discussing the use of glucose-lowering agents for persons with […]

McGill publishes evaluation of the MiniMed 670G HCL in a randomized controlled trial 

On January 1, Janet B. McGill, MD, MA, FACP, and collaborators had their work titled “Improved Glycemia with Hybrid Closed-Loop Versus Continuous Subcutaneous Insulin Infusion Therapy: Results from a Randomized Controlled Trial” published in “Diabetes Technology and Therapeutics.”  The focus was “to evaluate safety and effectiveness of MiniMed™ 670G hybrid closed loop (HCL) in comparison […]

Urano publishes review on the role of endoplasmic reticulum in diabetes 

In January, Fumihiko Urano, MD, PhD and collaborator, Shuntaro Morikawa had their research review titled “The Role of ER Stress in Diabetes: Exploring Pathological Mechanisms Using Wolfram Syndrome,” published in the “International Journal of Molecular Sciences.”  Endoplasmic reticulum (ER) is an important cytosolic organelle that contributes to the folding and processing of new secretory proteins, […]

McKee and Zhang publish review on the infectious complications of diabetes 

On January 1, Alexis McKee, MD and Rong Mei Zhang, MD had their review titled “Sickeningly Sweet: Infectious Complications of Diabetes” published in the “Clinical Microbiology Newsletter.”  Diabetes mellitus is incredibly common in the United States and has a high occurrence of infectious complications. These complications cause an increase in morbidity, mortality, and utilization of the […]

Herrick publishes study on social determinants in health documentation 

Cynthia Herrick, MD, FACP

In February, Cynthia Herrick, MD and colleagues had their research titled “The adoption of social determinants of health documentation in clinical settings,” published in “Health Services Research.”  The study was focused on understanding “the frequency of social determinants of health (SDOH) diagnosis codes (Z-codes) within the electronic health record for patients with prediabetes and diabetes […]

McKee publishes article on continuous glucose monitoring 

On December 19, Alexis M. McKee, MD, CDCES, published an article on “EndocrineWeb,” titled “Is Continuous Glucose Monitoring for You?”  The first continuous glucose monitor (CGM) came to existence in the early 2000s. The prior method of blood sugar testing at the time was fingerstick glucose reading. “By 2016, the accuracy of CGM sensors was so […]