Tag: wolfram syndrome

Urano publishes research on the connection between loss of WFS1 function and ER stress-mediated inflammation

On March 25, Fumihiko Urano, MD, PhD and colleagues had their research titled “Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells,” published in “Frontiers in Endocrinology.”  Wolfram syndrome is “a rare genetic disorder characterized by juvenile-onset diabetes mellitus, optic nerve atrophy, hearing loss, diabetes insipidus, and progressive neurodegeneration.” The main cause […]

Urano publishes case report on Wolfram syndrome

Fumihuko Urano, MD, PhD

On January 12, Fumihiko Urano MD, PhD and co-authors had their case report titled “Two Cases of Wolfram Syndrome Who Were Initially Diagnosed With Type 1 Diabetes” published in “AACE Clinical Case Reports.”  The report describes two genetically confirmed cases of Wolfram syndrome, “a rare endoplasmic reticulum disorder characterized by insulin-dependent diabetes mellitus, optic nerve […]