Urano Lab

The ultimate goal of our research is to find a cure for Wolfram syndrome, a prototype endoplasmic reticulum disease. Wolfram syndrome is a rare autosomal recessive genetic disorder with clinical signs apparent in early childhood. This condition is characterized by juvenile-onset diabetes, optic nerve atrophy, deafness, diabetes insipidus and neurodegeneration, and it may result in death in middle adulthood.