Bambouskova Lab

Our lab studies metabolic pathways that support and regulate immune cell activation. We focus on the function of metabolites and cellular metabolic processes that interplay with inflammatory signaling in immune cells, particularly in macrophages. We are also interested in how systemic metabolism affects immune cell functions in the context of obesity and the onset of T2D. Our lab uses molecular biology and biochemistry techniques together with systems approaches to tackle crosstalk between metabolism and immune cell signaling to better understand mechanisms underlying inflammatory diseases.