On February 10, Maria S. Remedi, PhD and colleagues had their abstract titled “Hyperexcitability reduces TRPM5 in pancreatic β-cells: Insights into disruption of insulin secretion in chronically stimulated islets,” published in Biophysical Journal. “Acute inhibition of ATP-sensitive K+ (KATP) channels in pancreatic β-cells result in depolarization, Ca2+ influx, and insulin secretion.” Throughout their research, the […]
Remedi and colleagues offer insight to insulin secretion disruption associated with KATP loss
