Maria S. Remedi, PhD and Esmeralda Castelblanco, PhD recently attended the 2024 60th Annual Meeting hosted by the European Association for the Study of Diabetes (EASD). The four-day meeting took place in Madrid, Spain from September 10-13, welcoming over 12,300 participants from more than 130 countries. Congratulations to Dr. Castelblanco on delivering an exceptional talk […]
Congratulations to Irfan Lodhi, PhD; Jeffrey R. Millman, PhD; Maria S. Remedi, PhD; and Julie M. Silverstein, MD of Washington University’s Division of Endocrinology, Metabolism and Lipid Research on achieving full professorship in their scientific and medical careers! The doctors were proudly joined by their colleagues on Thursday, August 22 to honor and celebrate their […]
On February 10, Maria S. Remedi, PhD and colleagues had their abstract titled “Hyperexcitability reduces TRPM5 in pancreatic β-cells: Insights into disruption of insulin secretion in chronically stimulated islets,” published in Biophysical Journal. “Acute inhibition of ATP-sensitive K+ (KATP) channels in pancreatic β-cells result in depolarization, Ca2+ influx, and insulin secretion.” Throughout their research, the […]
On February 7, Guifang Dong, PhD; Sangeeta Adak, PhD; Qiang Zhang, PhD; Chu Feng, MS; Li Yin, MD; Sarah Speck; Shuntaro Morikawa; Rie Asada, PhD; Fumihiko Urano, MD, PhD; Maria Remedi, PhD; Xiaochao Wei, PhD; Clay Semenkovich, MD; and collaborators had their work published in “Cell Metabolism.” “Hyperinsulinemia often precedes type 2 diabetes,” and palmitoylation, […]
On January 11, Semenkovich Lab and collaborators, had their research titled “Palmitoylation couples insulin hypersecretion with β cell failure in diabetes,” published in “Cell Metabolism.” Hyperinsulinemia is known to often come before type 2 diabetes. In the study, they explain how acyl-protein thioesterase 1 (APT1) knockdown in nondiabetic islets causes insulin hypersecretion. By using palmitoylation proteomics, their […]
On February 23, Maria S. Remedi, PhD and collaborators had their findings published in “Diabetes,” titled “ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm?” The article is meant to assess if adenosine triphosphate-sensitive potassium (KATP) channels are a new and effective way of thinking, in regard to hyperinsulinism and type […]