Many members of the Division of Endocrinology, Metabolism and Lipid Research participated at the American Diabetes Association‘s 84th Scientific Sessions, which took place in Orlando, Florida from June 21-24. Those members include Esmeralda Castelblanco Echavarria, PhD; Kai Jones, MD; Jeffrey R. Millman, PhD; Max C. Petersen, MD, PhD; R. Mei Zhang, MD; and Wei Zhang, PhD.
As the world’s largest meeting on diabetes, the sessions have welcomed colleagues and experts from over 115 countries to promote collaboration and scientific advancement in the field. The sessions encompassed eight theme areas that allowed attendees to learn about the latest scientific findings, groundbreaking research presentations, and to experience the exhibit and poster halls with the intention of accelerating the progression toward diabetes prevention and finding a cure.
Division Participants
Esmeralda Castelblanco Echavarria, PhD
Poster Presentation
Theme Area: Clinical and Preclinical Pancreas Immunology and Islet function
Session: Beta Cell Signal Transduction
Restoring beta-cell Mass and Identity in KATP-Induced Neonatal Diabetes – The Synergy of Autophagy and Intermittent Fasting
Kai Jones, MD
Oral Presentation
Theme Area: Clinical Diabetes/Therapeutics
Session: “New Technology—What’s New?”
Breath Acetone Correlates with Capillary Beta Hydroxybutyrate in Type 1 Diabetes
Jeffrey R. Millman, PhD
Oral Presentation
Theme Area: Immunology/Beta-Cell Replacement
Session: The “Barrier Reef”—Overcoming Hurdles to Beta-Cell Replacement Therapies Overcoming Islet Scarcity through In Vitro Differentiation of Human Pluripotent Stem Cells
Dr. Millman also participated in an expert panel discussing the heterogeneity of type 1 diabetes (T1D), covering topics such as beta cell pathology, T1D prevention, and insulin replacement. He was one of the experts selected to later present a summary of the panel discussion. In addition, Dr. Millman joined a public panel on the subject and will be co-authoring a review article with his co-panelists to further disseminate their findings.
Max C. Petersen, MD, PhD
Poster Presentation
Theme Area: Insulin Action/Molecular Metabolism
Session: Metabolite Transport and Molecular Metabolism
Effect of Dapagliflozin on Blood and Breath Ketones During Supervised Insulin Withdrawal in Adults with Type 1 Diabetes
Oral Presentation
Theme Area: Obesity/Integrated Physiology
Session: Risk Factors Reimagined—Beyond Obesity in Metabolic Risk
Plasma Lipidome in People with Insulin-Sensitive and Insulin-Resistant Obesity
R. Mei Zhang, MD
Poster Presentation
Theme Area: Behavioral Medicine, Clinical Nutrition, Education, and Exercise
Session: Type 2 Diabetes and Exercise—Where Do We Stand?
Acute Hyperglycemia Induces Human Podocyte Apoptosis by Increasing Monocyte Release of TNF-a Through ER Stress/ROS Activation of ADAM17/iRhom2 Expression
Wei Zhang, PhD
Oral Presentation
Theme Area: Insulin Action/Molecular Metabolism
Session: Novel Regulators of Insulin Action and Insulin Sensitivity
Depalmitoylation Inhibition Improves Glucose Tolerance by Promoting Endothelial Insulin Transcytosis
Additionally, Dr. Zhang was named a recipient of the Young Investigator Award and received one of the top scores within the program.