Bourey defines barriers in sleep medicine and weight management

On October 4, the American Academy of Sleep Medicine published an article titled “How weight loss medications are changing the sleep field,” featuring an interview with  Raymond E. Bourey, MD, FAASM. Dr. Bourey has board certification, 25 years in sleep medicine, and is an Associate Professor of Medicine with WashU Medicine’s Division of Endocrinology, Metabolism […]

Inaugural Repa-Eschen Lecture 

On Thursday, December 19, Washington University’s John T. Milliken Department of Medicine hosted their Medicine Grand Rounds event series at the Clopton Auditorium. During which the first-ever Repa-Eschen Lecture took place with presenting speaker Clay F. Semenkovich, MD, Chief of the Division of Endocrinology, Metabolism and Lipid Research, Irene E. and Michael M. Karl Professor of […]

Understanding muscle insulin resistance in metabolic syndrome 

In March, Samantha Adamson, MD, PhD; Sangeeta Adak, PhD; Max C. Petersen, MD, PhD; Dustin Higgins, DO; Larry D. Spears, PhD; Rong Mei Zhang, MD; Andrea Cedeno, MD; Alexis McKee, MD, CDCES; Aswathi Kumar, MD; Sudhir M. Singh, MD;  Fong-Fu Hsu, PhD; Janet B. McGill, MD, MA, FACP; and Clay F. Semenkovich, MD had their […]

Meet the Researcher: Marlie Maestas 

Marlie Maestas, a fifth-year graduate student in the Millman Lab, recently published her first first-authorship in Nature Communications. The study, titled Identification of unique cell type responses in pancreatic islets to stress, detailed the responses of different pancreatic islet cell types to endoplasmic reticulum and inflammatory stress. Maestas and her colleagues used single-cell RNA sequencing […]

Hughes and Merrins receive substantial NIH grant to study metabolic signaling of beta cell primary cilium 

Recently, Jing Hughes, MD, PhD and her collaborator Matthew Merrins, PhD, of the University of Wisconsin-Madison, were awarded nearly four million dollars in funding from the National Institutes of Health (NIH) to support their joint research project titled “Metabolic signaling of the beta cell primary cilium.” The funding will stretch from July of 2024 to […]

Semenkovich describes model of type 2 diabetes in video series for World Diabetes Day

On November 14, Dr. Clay F. Semenkovich, Chief of the Division of Endocrinology, Metabolism and Lipid Research, participated in World Diabetes Day by joining in a YouTube series hosted by Cell Metabolism. In the series, Dr. Semenkovich discusses the paper “Palmitoylation couples insulin hypersecretion with β cell failure in diabetes,” published on February 7, 2023, […]

Remedi and colleagues offer insight to insulin secretion disruption associated with KATP loss

On February 10, Maria S. Remedi, PhD and colleagues had their abstract titled “Hyperexcitability reduces TRPM5 in pancreatic β-cells: Insights into disruption of insulin secretion in chronically stimulated islets,” published in Biophysical Journal.  “Acute inhibition of ATP-sensitive K+ (KATP) channels in pancreatic β-cells result in depolarization, Ca2+ influx, and insulin secretion.” Throughout their research, the […]

Akturk and McKee review emerging type 1 diabetes technologies and therapeutics 

On August 19, Halis Kaan Akturk, MD of the Barbara Davis Center for Diabetes at University of Colorado and Alexis M. McKee, MD of the Division of Endocrinology, Metabolism and Lipid Research at Washington University School of Medicine, had their review titled “Emerging Technologies and Therapeutics for Type 1 Diabetes,” published online by Science Direct. […]

Herrick investigates the effects of SDoH on glycemic control in low-income individuals with type 2 diabetes 

Cynthia Herrick, MD, FACP

On May 23, Cynthia Herrick, MD, MPHS and colleagues had their study titled “Food insecurity, SNAP participation and glycemic control in low-income adults with predominantly type 2 diabetes: a cross-sectional analysis using NHANES 2007–2018 data,” published by BMJ Open Diabetes Research and Care.  Food insecurity is one social determinant of health (SDoH) known to affect […]

Hogrebe, Ishahak and Millman review stem cell-derived islet replacement therapy for type 1 diabetes 

On May 4, Nathaniel Hogrebe, PhD; Matthew Ishahak, PhD; and Jeffrey Millman, PhD had their review titled “Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes,” published in Cell Stem Cell.  In diabetes treatment, there is great potential for islet-like endocrine clusters from human pluripotent stem cells (hPSCs) to provide a limitless […]