Hughes and Merrins receive substantial NIH grant to study metabolic signaling of beta cell primary cilium 

Recently, Jing Hughes, MD, PhD and her collaborator Matthew Merrins, PhD, of the University of Wisconsin-Madison, were awarded nearly four million dollars in funding from the National Institutes of Health (NIH) to support their joint research project titled “Metabolic signaling of the beta cell primary cilium.” The funding will stretch from July of 2024 to […]

Hughes receives CSCTR Early Career Development award

Jing Hughes, MD, PhD was recently selected as an awardee for the 2023 Early Career Development award, provided by the Central Society for Clinical and Translational Research (CSCTR). The organization develops and supports communication, collaboration and career development of medical researchers primarily located in the central region of the United States. The award recognizes and […]

Hughes and colleagues study cilia and Ca2+ waves in pancreatic islet leader beta cells  

In March, Jing Hughes, MD, PhD and colleagues had their work titled “Molecular phenotyping of single pancreatic islet leader beta cells by ‘Flash-Seq,’” published by Life Sciences.  Stimulation of insulin secretion occurs by high glucose from increases in cytosolic Ca2+ within pancreatic beta cells. Recent data has also shown that subpopulations of beta cells exist, […]

Hughes, Adamson, Petersen and Speck attend AAP, ASCI and APSA joint meeting 

During the weekend of April 21-23, Jing Hughes, MD, PhD; fellows Samantha Adamson, MD, PhD and Max Petersen, MD; and student Sarah Speck attended an annual meeting in Chicago, Illinois. The joint meeting was hosted by The Association of American Physicians (AAP), The American Society for Clinical Investigation (ASCI), and The American Physician-Scientists Association (APSA).  […]

Hughes Lab publishes article on motile islet cilia  

On September 23, Jing Hughes, MD, PhD and colleagues published their research titled “Islet primary cilia motility controls insulin secretion” in Science Advances.  “Primary cilia are thought of as immotile, mainly due to the lack of evidence of molecular motors. We have now found a missing link that explains why some primary cilia could, in […]